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[DOI] [PubMed] [Google Scholar] 39.Besterman H.S., Cook G.C., Sarson D.L., Christofides N.D., Bryant M.G., Gregor M., Bloom S.R

Clinical trials of GLP-1 medications, including the STEP program for semaglutide and SURMOUNT trials for tirzepatide, have documented improvements in physical function scores and quality of life measures

Common adverse effects are gastrointestinal and usually dose-related

If a fixed-dose combination is considered, extended-release options like Janumet XR Products may simplify regimens when appropriate

Subsequently, a detailed analysis of the relationship between GLP-1RAs and cardiomyopathy is conducted