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Gut microbiota interactions with anti-diabetic medications and pathogenesis of type 2 diabetes mellitus

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Options include holding the dose and not escalating further, dropping back to the previous dose, switching to the other medication, adding supportive medications for specific symptoms, or in rare cases, discontinuing treatment entirely

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Individuals with poorly controlled type 2 diabetes already carry an elevated background UTI risk due to glucosuria and impaired immunity

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Abstract Concerns over reports of suicidal ideation associated with semaglutide treatment, a glucagon-like peptide 1 receptor (GLP1R) agonist medication for type 2 diabetes (T2DM) and obesity, has led to investigations by European regulatory agencies

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