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Although there is a high volume of studies supporting these conclusions, the overall certainty of evidence is moderate because there are very heterogeneous outcome measures across studies, variable factors that control body composition, and the duration of interventions is often relatively short
Removing excess skin enhances physical comfort and improves the aesthetic outcome of weight loss
Altogether, extrapolating preclinical findings directly to a human setting is premature without further investigations
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D., Frangou E., Love S
