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Studies have shown (2) that some patients with PCOS taking metformin (at various doses) may lose up to 4% of their body fat over an 8-month period: This graph outlines the various dosages of metformin and how certain patients lost weight

However, the weight loss caused by GLP-1s can also lead to muscle loss if steps arent taken to protect muscle health

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Where you may have seen it: Tirzepatide is available under brand names like Mounjaro and Zepbound, both of which are used for weight management and improving metabolic health

Some patients use GLP-1 medications for a period of time to support weight loss and metabolic health, while others may stay on a maintenance dose