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9,12 Additionally, GLP-1RAs activate nitric oxide (NO) synthase expressed in Schlemms canal and the trabecular meshwork, increasing NO production to reduce trabecular meshwork contraction, improving aqueous outflow

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After each dose, the concentration follows an exponential decay: C(t) = C0 * e^(-0.693 * t / t_half), where C0 is the peak concentration from that dose, t is time since injection, and t_half is the half-life