glp-1 weight loss drug news today 2025 Overdoses Are Rising as Telehealth Weight-Loss Prescriptions Boom GLP-1 Drugs Revolutionize Weight Loss

Adding the 9mg arm suggests the sponsor believes the 8mg to 12mg range contains the optimal therapeutic dose and wants more granular data to identify it precisely

Human No human studies regarding the safety of GLP-1 agonists during lactation were found

The Semaglutide Treatment Effect in People with Obesity and Heart Failure with Preserved Ejection Fraction and Diabetes Mellitus (STEP-HFpEF DM) trial demonstrated that semaglutide significantly reduced body weight and improved HF-related symptoms and physical limitations in people with obesity-related HF with preserved ejection fraction and type 2 diabetes mellitus [93]

J Mol Endocrinol

Common Side Effects Most people who take GLP-1 medications experience mild digestive symptoms that often improve over time: Nausea: The most frequently reported side effect Diarrhea: Usually temporary as your body adjusts Stomach upset: Can be reduced by eating smaller meals Loss of appetite: This is actually part of how the medication works Serious but Rare Side Effects Some side effects are uncommon but require immediate medical attention: Thyroid tumors: Reported in less than 1 percent of patients Gallbladder problems: Including gallstones in some patients Severe stomach pain: Could indicate pancreatitis Kidney problems: Especially if you become dehydrated Patients should discuss all potential risks with their healthcare provider before starting any GLP-1 medication