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Moreover, it is increasingly recognized that weight loss itself primarily serves as a surrogate marker for favorable changes in body fat distribution, particularly reductions in ectopic fat depots such as visceral adipose tissue and intrahepatic lipid content, both of which are strongly associated with ASCVD risk (80, 81)

These modifications can activate latent susceptibility genes or repress protective regulatory loci, thereby altering immune cell function and promoting autoimmune reactivity

So far, were getting very similar results, he told me

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While the dashboard was referenced in a number of media reports over the last couple weeks, wed like to especially thank Mike Erman at Reuters, Ed Silverman at STAT News, Khristopher Brooks at CBS News, Noah Manskar at New York Post, Kate Ashford at Investopedia, and Darrel Rowland at Columbus Dispatch for highlighting the tool, as well as correctly providing some of the nuances at play in the marketplace