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Alternatively, another three residues (D21 P -F22 P -W25 P ) compacted well with the ordered ECL1 of GLP-1R via a hydrogen bond with Q210 ECL1 and packing with W214 ECL1

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Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5-adenosine mono- phosphate-dependent protein kinase A and a phosphatidylinositol 3-kinase-dependent pathway

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