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9,10 Among similarly designed placebo-controlled trials, treatment with semaglutide at 2.4 mg per week resulted in 73% and 92% of individuals with and without T2D achieving 5% or greater body weight by 68 weeks, respectively (efficacy estimands)

Up to 15-22% weight loss after 6-12 months of continuous use

Novo Nordisk has been conducting studies on semaglutide (marketed as Wegovy for weight loss and Ozempic for diabetes) and it is reported to be in a late-stage trial targeting MASH

Women, particularly premenopausal women, tend to store more subcutaneous fat in the gluteal-femoral region due to estrogen's influence on fat deposition

Results with Mounjaro for PCOS are not the same for everyone