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has announced that China's National Medical Products Administration (NMPA) has approved mazdutide, a first-in-class dual glucagon (GCG)/glucagon-like peptide-1 (GLP-1) receptor agonist, for chronic weight management in Chinese adults with overweight or obesity

Summary Millions of people are now using GLP-1 medicines

This enhanced GCG receptor activity, combined with the effects of GIP receptor engagement, is believed to contribute to the superior weight loss observed with this triple agonist

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The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon