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[162] In March 2023, a Novo Nordisk official said, based on a randomized, double-blind study (NCT03548935 [163] ) funded by the company, that people using semaglutide to lose weight regained two-thirds of their original weight loss one year (52 weeks) after discontinuing use of the drug

In comparison with the overweight/obese reference group, which had a rate of major birth defects of 3.9%, the adjusted OR was 0.54 (95% CI, 0.11 to 2.75)

As a dual agonist, it targets both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Filippatos TD, Panagiotopoulou TV, Elisaf MS

Literature / References M.E
