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Galectin-1 accelerates high-fat diet-induced obesity by activation of peroxisome proliferator-activated receptor gamma (PPAR) in mice
Adjustments for potential confounding variables were made, though residual and unmeasured confounding is still a possibility
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Pregnancy considerations: Tirzepatide is not recommended during pregnancy, and women of childbearing potential should be advised that tirzepatide may reduce the effectiveness of oral contraceptives, particularly during initiation and dose escalation
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