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Jens Juul Holst, a Danish GLP-1 expert at the University of Copenhagen, later recalled Engs frustration to Science magazine in 2018: He was extremely frustrated

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Both medications are effective weight loss tools, but they function in slightly different ways: Semaglutide targets the GLP-1 receptor, mimicking the GLP-1 hormone to reduce appetite, slow digestion, and control blood sugar

As research continues to uncover new applications and refine our understanding of these medications, GLP-1 agonists will play an increasingly important role in preventive medicine and chronic disease management