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At the same time, prescribing trends shifted, with AOM semaglutide experiencing its largest monthly increase while AOM tirzepatide growth slowed and initiations declined

Efficacy and safety of once-weekly semaglutide versus exenatide ER in subjects with type 2 diabetes (SUSTAIN 3): A 56-Week, Open-Label, Randomized Clinical Trial

Falling estrogen levels shift fat storage from the hips and thighs to the abdominal area
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Dose escalation also impacts results
