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Ironically, these findings are coming to light in an era when their relevance is diminishing, with the advent of drugs (flozins and GLP1RAs) which can be safely used below GFR 30, and which also have evidence of clinical outcome benefits

But emotionally they had already become strangers

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For context, this is considerably more affordable than the injectable GLP-1 treatments, which can exceed $1,000 per month at retail without coverage

Ozempic, containing GLP-1, is primarily used for type 2 diabetes and functions differently from insulin