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Be Aware of Any Unwanted Side Effects During this gradual increase in dosage, patients should be aware of any unwanted side effects, such as: Excessive feelings of fullness that go beyond the desired results

Am J Physiol Cell Physiol 2011;300:C860-C871

In contrast, short-acting GLP-1RAs, such as lixisenatide, require more frequent dosing due to shorter half-lives, resulting in intermittent receptor stimulation that may reduce the risk of diarrhea

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Patients who switched were more likely to continue treatment and showed higher adherence than those who remained on their initial medication, suggesting adjustments often reflected active management
