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Description
Adding GIPR co-agonism (as in tirzepatide and retatrutide) introduces additional Gs signalling from a second receptor type expressed on adipocytes, beta cells, and hypothalamic neurones
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First, gastrointestinal distress: tirzepatide's most common side effects are nausea (up to 31% of patients in SURPASS trials), vomiting, diarrhea, and decreased appetite

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At Set Point, Troy Watson will help you determine the best timing for your injections, ensuring that your weight loss or diabetes management goals are met efficiently and effectively
Qiao L, Kinney B, Schaack J, Shao J