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Recent clinical trial results: A number of high-profile clinical trial findings have driven a material change in the perception of how these drugs may be used in the future
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In individuals with T2DM, chronic hyperglycemia is known to downregulate GIPR expression and impair GIP-stimulated insulinotropic activity, thereby limiting the efficacy of GIP monotherapy [21]
Freemark M, Bursey D
The fermentation of fiber in the gut leads to the production of short-chain fatty acids, which can stimulate GLP-1 secretion
