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These changes create a foundation that minimizes gastrointestinal distress once the medication kicks in
None of these drugs work as well as semaglutide or tirzepatide, experts say, but they may help with weight loss maintenance

Obesity causes persistent fatigue through sleep apnea, chronic inflammation, insulin resistance, reduced cardiovascular capacity, and joint pain that limits activity

95% CI, 1.231.52) [64]

In addition, not every patient requires the full therapeutic dose to achieve improvements in glucose control or weight reduction