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Prior studies have identified EIF3H as a critical deubiquitinase of YAP, utilizing a unique catalytic triad (Asp90, Asp91, and Gln121) and key residues (Trp119 and Tyr140) that interact with the Nterminal region of YAP1 to form a stable complex, thereby promoting YAP deubiquitylation, stabilization, and transactivation
1966 Feb [cited 2019 Jul 19];11(2):15572
These steps support the bodys natural processes without the need for additional chemicals
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