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Abstract Glucagon-like peptide-1 receptor (GLP-1R) activation promotes insulin secretion from pancreatic beta cells, causes weight loss, and is an important pharmacological target in type 2 diabetes (T2D)

doi: 10.2337/ds16-0026 47 PauzaAGThakkarPTasicTFelippeIBishopPGreenwoodMPet al

Disturbi alimentari e GLP-1 agonisti Nellambito dei DCA, la ricerca ha iniziato a indagare la possibilit che i farmaci GLP-1 agonisti possano essere utilizzati, in certi casi, anche per il trattamento di disturbi dellalimentazione

GLP-1s are not going anywhere pharma manufacturers continue to evolve their GLP-1/GIP product offerings (e.g., Eli Lillys Zepbound is the newest on the market), and the number of addressable indications is increasing (e.g., recent clinical evidence that may merit further FDA approval of GLP-1s for cardio-metabolic, nephrological and neurological indications)

Hybrid care models integrating pharmacotherapy with lifestyle support show promise for sustainable outcomes ( 3.2 Divergent muscle outcomes in weight loss interventions