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95 There is a lack of knowledge on GLP-1RAs precise effect on neurogenesis
Phase 3 trial results (REDEFINE program) showed CagriSema produced approximately 22-25% body weight reduction, putting it in direct competition with tirzepatide and retatrutide
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While extensive data reassure their use, more trials are needed, particularly for populations like children, older adults, and those with severe illness
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