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Concurrently, improved insulin sensitivity suppresses adipose tissue lipolysis and reduces circulating free fatty acid concentrations [57]

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Exenatide (Ex-4) and liraglutide are effective in modulating key pathways involved in neurodegeneration, such as apoptosis, mitochondrial function, and autophagy, in models of AD and PD

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These medications include semaglutide (marketed as Ozempic for diabetes and Wegovy for weight management), liraglutide (Victoza for diabetes and Saxenda for weight management), dulaglutide (Trulicity for diabetes), and tirzepatide (Mounjaro for diabetes), which combines GLP-1 action with glucose-dependent insulinotropic polypeptide (GIP) receptor agonism