glp 1 liver enzymes GLP-1 Receptor Agonist and Non-Alcoholic Fatty Disease Glucagon‐like peptide‐1 receptor agonists (GLP‐1

Collaboration NCDRF

MASH, previously called nonalcoholic fatty liver disease, happens when excessive fat buildup in the liver leads to scarring and inflammation

The pancreas and central nervous system, specifically hypothalamic structures, have been shown to robustly and directly respond to GLP-1R agonism, mediating anti-diabetic and anti-obesogenic physiology and behaviors, respectively

5.3 Increased Blood Pressure and Heart Rate CNS stimulants cause an increase in blood pressure (mean increase about 2 to 4 mm Hg) and heart rate (mean increase about 3 to 6 bpm)

Lab testing and vital signs may help providers understand metabolic health and determine whether treatment may be beneficial