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By stimulating GLP-1 receptors in the hypothalamus and brainstem, tirzepatide slows gastric emptying (though this effect may diminish over time), prolongs the feeling of fullness after meals, and reduces hunger signals

For someone starting at 250 pounds, this translates to 37-50 pounds of weight loss enough to dramatically change body proportions and potentially create areas of loose skin

And Ive seen what happens when men reach the end of it without anything built underneath

However, it is important to emphasize that tirzepatide is not approved for, nor specifically designed to treat, autoimmune diseases

Lancet Diabetes Endocrinol 8(10):845854