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In the case of children it can have a profound impact on their school performance, with many facing bullying and discrimination
The review revisited SUSTAIN-6, where semaglutide-treated patients showed a hazard ratio of 1.76 for retinopathy complications compared with placebo. The discussion has since shifted toward whether rapid metabolic changerather than direct retinal toxicitymay explain the signal
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doi:10.1056/NEJMoa2410819 16
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