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Zepbound Important Safety Information: Read more about serious warnings and safety info

However, the underlying mechanisms of these effects cannot be fully explained by lower blood glucose levels or increased GLP-1 bioavailability or signaling, and has to be further elucidated

Offer subcutaneous semaglutide up to 1 mg once weekly for CV, renal and glycaemic benefits (no specific guidance on tirzepatide or oral semaglutide because CVOT results were unavailable at time of review)

Some patients may take semaglutide (Ozempic) off-label for weight loss

What This Means for Patients who Use GLP-1s Health coverage varies a lot across different regions, providers, and plans