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Statements Author contributions XH: Conceptualization, Data curation, Formal Analysis, Methodology, Writingoriginal draft

Plenty of people with high BMIs are also healthy

Your provider will help you consider your dosage, lifestyle, and alternative options

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This triple mechanism distinguishes it from existing approved agents semaglutide, for example, acts on the GLP-1 receptor only, whilst tirzepatide is a dual GIP/GLP-1 receptor agonist and is being investigated to determine whether broader receptor engagement offers additional metabolic benefit