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The choice between tablets and injections depends on personal preference, tolerance, and how well the oral formulation works for each individual patient

E., Sanchez-Watts, G

Medications like orforglipron (an oral, non-peptide GLP-1 agonist), survodutide (a dual glucagon/GLP-1 agonist), and CagriSema (combining cagrilintide with semaglutide) are advancing through clinical trials

For recruitment assays, INS-1 832/3 GLP-1R KO cells were seeded onto 6-well plates and transiently transfected with a combination of 1 g GLP-1R-SmBiT WT or V229A and either 1 g of LgBiT-mini-G s , -mini-G q or --arrestin 2