glp 1 agonist benefits Frontiers The expanding benefits of GLP-1

A recent in vivo study in healthy subjects showed that acute intravenous infusion of GLP-1 during a pancreatic clamp, in which insulin and glucagon levels were maintained at basal levels, caused a reduction in hepatic glucose production, suggesting a potential direct effect on gluconeogenesis [11]

Given that different GLP-1 receptor agonists have different dosing recommendations (Table 1), it is important that patients switching between such agents are counseled on any applicable changes to their previous regimen

Diabetes status affects results modestly

MACE 3P, 3-point cardiovascular composite episode

Gastroenterology (2002) 122(2):53144