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Liu S-C, Yang S-F, Yeh K-T, Yeh C-M, Chiou H-L, Lee C-Y, et al

Fibrosis-4 index (FIB-4) decreased marginally in the exenatide group (0.10 0.26, p = 0.0448)
However, the FDA has received voluntary reports from patients describing emotional numbness, reduced motivation, and depressive symptoms after starting GLP-1 therapy, though causality remains unclear

Ghrelin stimulates appetite, imagination of food, GH, ACTH and cortisol, but does not affect leptin in normal controls

Effects of Weight Loss on Metabolic Adaptation
