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doi: 10.1210/endo.139.5.5998 151 ZhuTLiCZhangXYeCTangSZhangWet al

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Foundayo: In latestage trials, participants taking the 17.2 mg dose lost about 12% of their body weight over roughly 72 weeks, compared with about 2% in the placebo group

Metabolic adaptation and set point defense Your body has what researchers call a defended body weight, a range it tries to maintain through metabolic adjustments