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Participants who lost an average of 20.9% during a 36-week lead-in period were then randomized to continue tirzepatide or switch to placebo for 52 additional weeks

The goal is to find the lowest effective dose that achieves the desired outcomes, whether that is primarily weight loss, inflammation reduction, or both

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For liraglutide, out of the total reported suicidal events, 47% occurred with liraglutide (48/102