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The first GLP-1 analog was approved for the treatment of type 2 diabetes in 2005 Trusted Source PubMed Central Go to source

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Endocr Rev 30(6):557585 Langenberg C, Sharp SJ, Franks PW et al (2014) Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

The discontinued NCT02472717 trial investigating liraglutide in PsA further illustrates both the pioneering nature and the challenges inherent in this research field ( Importantly, none of the currently available trials specifically target the early PsA window, which is increasingly recognized as a critical period for disease modification

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