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Description
GLP1 receptor agonists have changed the way we treat type 2 diabetes and obesity, offering powerful glucose-lowering effects and sustained weight loss
As a result of these combined effects, most patients with T2D using GLP-1RAs experience an improvement in fasting serum insulin and insulin sensitivity (homeostasis model assessment for insulin resistance), a lowering of hemoglobin A1c levels, and a decreased reliance on supplemental insulin (12, 31)

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24 Afferent signalling is further communicated through neural contacts between brainstem nuclei, the hypothalamus and forebrain regions associated with integration of visceral sensory information as well as coordination of autonomic function and behavioural responses
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