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Endpoints The primary cardiovascular efficacy endpoint was a composite of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke, assessed in a time-to-first-event analysis

Finally, there were differences in trial designs, patient characteristics, background therapy, and endpoint definitions

Weight loss: 3 to 8% of body weight over 3 to 6 months for users who respond

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Thats why GLP-1 is usually thought of as a longer-term treatment, and the transition (if you do stop) belongs under medical supervision, together with nutrition, movement and regular check-ups