glp 1 and ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, gut microbiome: RCT: Cell Reports Medicine Synergistic Effects of the Ketogenic

In 2023, the sales of Novo Nordisks Ozempic crossed $13.9 billion

Muscle preservation during GLP-1 or medical weight-loss treatment depends heavily on protein intake, resistance training, adequate nutrition, dose management, sleep, hormones, and medical monitoring

Ozempic works by slowing gastric emptying and suppressing appetite

In older or frail populations, concerns include lean-mass loss, aspiration risk during procedures, sarcopenia, falls, and worsening dysphagia

Citations Klausen MK et al, "Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial." The Lancet, May 2, 2026