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Several, independent meta-analyses have reported that the majority of patients with bipolar disorder experience problems with memory loss and cognition across all phases of the disorder, even during periods of remission in a manner that increases with recurrence [101,102,103]

The mechanism appears to involve insulin resistance at the L-cell itself

The effects of valproic acid from a biological perspective are multiple

The most frequently reported side effects are gastrointestinal, including nausea, vomiting, and diarrhea

[DOI] [PubMed] [Google Scholar] 71.Hayes MR, Skibicka KP, Grill HJ
