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Efficacy and weight change are approximate averages from clinical trials

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Athar W, Card ME, Charokopos A, et al

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Research published in peer-reviewed journals estimates that patients lose approximately 7% of midfacial volume for every 10 kilograms of total weight loss , with the effect concentrated in the areas that contribute most to a youthful appearance

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no clinical trial data exist for this pairing, though their complementary amylin and incretin-based mechanisms provide a theoretical scientific rationale

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