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Za lijenike je potrebno razumno procijeniti imbenike rizika pacijenata i formulirati personalizirane planove lijeenja

12 Figure 23: SF-36v2 change from baseline at week 26, PIONEER 2 (FAS) CI = confidence interval

Treatment discontinuation due to an adverse event occurred in 7.0% of enrolled participants during the 36-week open-label lead-in treatment period, mainly due to gastrointestinal events

Although an association with urinary congenital malformations was identified, it was based on limited unadjusted data and may reflect confounding by maternal diabetes or obesity rather than a true treatment effect

This couplingintense but typical athletic training alongside appetite suppression from semaglutideencourages muscle loss along with reductions in body fat, altering body composition for the worse
