glp 1 gip dual agonist weight loss TrimRX GIPR/GLP-1R dual agonist therapies for

Narayan KM, Boyle JP, Geiss MA, et al

Neuropsychopharmacology 42, 23872397

In the HARMONY-2 (efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide) clinical study, patients were randomized to receive either once-weekly albiglutide (30 mg, titrated up to 50 mg if required for glycemic control) or 10 units of insulin glargine once daily

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Lastly as the majority of GLP-1 RAs in this study were semaglutide, this may not apply to all GLP-1 RAs and additionally, because the analysis excluded over 26,000 patients who could not be matched, the results may not apply to the full spectrum of patients taking these drugs in the real world, particularly those with more complex health profiles. MNT spoke with David I