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194 people with Parkinsons disease participated in the trial across six research hospitals in the UK, including in London, Oxford, Plymouth, Salford and Edinburgh

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Additionally, examination of publication bias indicated a symmetrical distribution in the funnel plot, suggesting the absence of publication bias

These compounds reduce central neuroinflammation by lowering interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-), and limiting oxidative stress ( On the other side, current trends in precision psychiatry aim to classify subpopulations of patients with inflammatory depression, characterized by elevated markers of inflammation, increased glucose and lipid levels, neurovegetative symptoms, anxiety or irritability, and suicidal ideation (Wessa et al., 2026)