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Feeling peckish

FDA approves Novo Nordisks first oral GLP-1 pill Wegovy for obesity, offering an injection-free option and improving long-term treatment adherence.

The Wonders of CREATINE from Mature Muscle Podcast (38 min) Published Jun 21, 2025

This incretin hormone plays several crucial roles in metabolic health: Stimulates insulin secretion from the pancreas in a glucose-dependent manner Suppresses glucagon release (which helps prevent blood sugar spikes) Slows gastric emptying, promoting longer feelings of fullness Reduces appetite by acting on brain centers that control hunger Improves beta-cell function in the pancreas The natural GLP-1 hormone has a very short half-life (12 minutes) in the bloodstream because it is rapidly broken down by an enzyme called dipeptidyl peptidase-4 (DPP-4)

With a little effort, Wegovy will work for weight loss.