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The trials included 50 patients 2 years of age with measurable recurrent diffuse midline glioma (DMG) that harbored H3 K27M mutation who had received prior radiation therapy

Notify your doctor if you experience: Anxiety Buzzing or ringing in ears Chest discomfort Confusion or trouble concentrating Depression Dry mouth Fainting Hallucinations Headaches Hyperventilation Impulsivity Irregular heartbeats Irritability Lightheadedness Mood or mental changes Restlessness Seizures Shaking Skin hives, rashes, or itching Suicidal thoughts Sweating Trouble sleeping Unusual tiredness Vision changes or eye pain Stop using Contrave and get medical help immediately if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat

However, colonoscopy remains the gold standard for comprehensive evaluation, particularly in patients 45 and older or those with alarm features

Arnold MT, Dai A, Graber Y, Pachecoi-Lopez M, Langhans G

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