glp-1 receptor agonist and dpp-4 inhibitor combination not recommended Comparison of agonists inhibitors It's the first in a

These include canagliflozin (Invokana), dapagliflozin (Farxiga) and empagliflozin (Jardiance)

But they work through different hormonal pathways

A statistical analysis assimilated various studies which insisted that GLP-1 agonists play a pivotal role in regulating menstrual cycle, ameliorating pregnancy rates and addressing infertility, a key concern in PCOS, though these benefits appeared to be temporary as drugs were only prescribed for 12 weeks and IVF pregnancies were unaffected

RR, risk ratio

To avoid or minimize these effects, the medications are started at a low dose and then ramped up slowly over a few months