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These 2 forms result from tissue-specific differences in posttranslational processing of the preproglucagon gene product

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This finding could suggest that the elevation of GLP-1 was present before the stroke

A meta-analysis of 12 randomized controlled trials (n = 17,996) further confirmed these renoprotective effects, with agents structurally closer to endogenous human GLP-1, such as semaglutide, showing the strongest benefit (RR = 0.78, 95% CI: 0.710.85) ( 3.4 Hepatic protection In clinical practice, semaglutide has demonstrated notable efficacy in resolving NASH without aggravating hepatic fibrosis

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