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UK GLP-1 users report increased confidence, deeper intimacy, and new romantic opportunities, highlighting the emotional effects of weight loss medications.

At the same time, payer policies often require discontinuation of GLP-1 therapy when a patients BMI drops below a set threshold, inadvertently triggering a frustrating cycle of weight loss and regainthe so-called yo-yo effect. This not only impacts ongoing adherence and persistence but also undermines the long-term cost-effectiveness of these therapies for healthcare systems

This has increased interest in pharmacological treatment options

GLP-1 drugs are the first medication to show promise for treating addiction to a wide range of substances.

However, peptides are readily broken down during digestion which is why Ozempic (approved for diabetes) and Wegovy (just a higher dose of semaglutide approved for weight loss) have to be injected