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A new analysis is raising concerns about Wegovy, the blockbuster weight-loss drug, after researchers found it may carry the highest risk of a rare eye stroke that can cause sudden vision loss

The authors found that the number of GLP-1 expressing cells is consistently reduced at the site of active disease in both mouse models of intestinal inflammation and in CD patients, as confirmed by the single-cell RNA sequencing data

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Eli Lilly and Company has registered its intent to carry out a Phase 3b clinical trial that will see the companys tirzepatide (Mounjaro) compared with Novo Nordisks semaglutide (Wegovy) 2.4mg in 700 adult participants who have obesity or overweight with weight related comorbidities without Type 2 diabetes

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