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Recent improvements in molecular modeling have enabled the design of new inhibitors with higher selectivity for DPP-4 than for other dipeptidyl peptidases, thus minimizing side effects [28]

GLP-1 medications like Ozempic, Wegovy, Trulicity, and Mounjaro have become powerful tools for managing type 2 diabetes and supporting weight loss

In addition, because the studies participants had severe hyperglycaemia, metformins glucose-lowering effect may have also been related to changes in peripheral insulin sensitivity, but this was not measured in those studies

Since people with diabetes are at higher risk for cardiovascular diseases, improving heart health can lessen the reliance on medications that address these risks

3163 In Re: Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) Non-Arteritic Anterior Ischemic Optic Neuropathy Products Liability Litigation