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Glucagon-Like Peptide-1 Reduces Hepatic Lipogenesis via Activation of AMP-Activated Protein Kinase

Initial clinical findings suggest that GLP-1 receptor agonists could provide an effective therapeutic strategy in patients with AD and those at risk, however, there remains a lack of sufficient evidence in large clinical samples to draw any firm conclusions

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The mechanisms are not fully understood but may involve delayed gastric emptying, activation of the area postrema in the central nervous system, changes in nutrient absorption, and altered intestinal motility [116,117,118]